Hypothalamic Pituitary Axis

How Long-Term Steroid Use Affects the Hypothalamic Pituitary Axis

Long-term steroid use suppresses your Hypothalamic Pituitary Axis by mimicking natural cortisol, causing your brain to reduce hormone production. It leads to decreased CRH from your hypothalamus and reduced ACTH from your pituitary gland. Over weeks to months, your adrenal glands atrophy, resulting in symptoms like fatigue, weakness, and poor stress response. Recovery varies from […]

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Electrolytes and Kidney Function

How to Keep Electrolytes and Kidney Function in Balance During High-Dose Cycles

To keep your kidneys safe while managing electrolytes during high-dose cycles, you need to do it all the time. You should drink 3–4 liters of water every day, keep an eye on your sodium and potassium levels, and take nephroprotective supplements like NAC and milk thistle. Look out for warning signs like muscle cramps, feeling

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